EXPLOITING NECROPTOSIS FOR THERAPY OF ACUTE LYMPHOBLASTIC LEUKEMIA

Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia

Escape from chemotherapy-induced apoptosis is a hallmark of drug resistance in cancer.The recent identification of alternative programmed cell death pathways opens up for possibilities to circumvent the apoptotic blockade in drug resistant cancer and eliminate malignant cells.Indeed, we have recently shown that programmed Training necrosis, termed

read more